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Review
. 2013:2013:502194.
doi: 10.1155/2013/502194. Epub 2013 Aug 21.

Skeletal muscle oxygen saturation (StO2) measured by near-infrared spectroscopy in the critically ill patients

J Mesquida  1 , G Gruartmoner, C Espinal
Affiliations
Review

Skeletal muscle oxygen saturation (StO2) measured by near-infrared spectroscopy in the critically ill patients

J Mesquida et al. Biomed Res Int. 2013.

Abstract

According to current critical care management guidelines, the overall hemodynamic optimization process seeks to restore macrocirculatory oxygenation, pressure, and flow variables. However, there is increasing evidence demonstrating that, despite normalization of these global parameters, microcirculatory and regional perfusion alterations might occur, and persistence of these alterations has been associated with worse prognosis. Such observations have led to great interest in testing new technologies capable of evaluating the microcirculation. Near-infrared spectroscopy (NIRS) measures tissue oxygen saturation (StO2) and has been proposed as a noninvasive system for monitoring regional circulation. The present review aims to summarize the existing evidence on NIRS and its potential clinical utility in different scenarios of critically ill patients.

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Figures

Figure 1
Figure 1
StO2 response to a vascular occlusion test (VOT). The transient ischemia generates two main parameters: the deoxygenation response (DeO2) and the reoxygenation response (ReO2). StO2: tissue oxygen saturation; DeO2: deoxygenation slope; ReO2: reoxygenation slope.
See this image and copyright information in PMC

References

    1. Mesquida J, Borrat X, Lorente JA, Masip J, Baigorri F. Objectives of hemodynamic resuscitation. Medicina Intensiva. 2011;35(8):499–508. - PubMed
    1. den Uil CA, Lagrand WK, van der Ent M, et al. Impaired microcirculation predicts poor outcome of patients with acute myocardial infarction complicated by cardiogenic shock. European Heart Journal. 2010;31(24):3032–3039. - PubMed
    1. de Backer D, Creteur J, Preiser J, Dubois M, Vincent J. Microvascular blood flow is altered in patients with sepsis. American Journal of Respiratory and Critical Care Medicine. 2002;166(1):98–104. - PubMed
    1. de Backer D, Donadello K, Sakr Y, et al. Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome. Critical Care Medicine. 2013;41(3):791–799. - PubMed
    1. Trzeciak S, McCoy JV, Dellinger RP, et al. Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis. Intensive Care Medicine. 2008;34(12):2210–2217. - PMC - PubMed