Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Sep 13;341(6151):1175.
doi: 10.1126/science.1241266.

Comment on "Influence of HLA-C expression level on HIV control"

Elisa Lo Monaco  1 , Elisa Tremante, Priscilla Biswas, Martin P Cranage, Donato Zipeto, Alberto Beretta, Patrizio Giacomini
Affiliations
Free article
Comment

Comment on "Influence of HLA-C expression level on HIV control"

Elisa Lo Monaco et al. Science. .
Free article

Abstract

Apps et al. (Reports, 5 April 2013, p. 87) found that high human leukocyte antigen C (HLA-C) expression favors HIV-1 control. However, as noted here, HLA-C was assessed with a monoclonal antibody (DT9) that cross-reacts with HLA-E. In the context of the available evidence, this is consistent with the idea that the two leukocyte antigens collaborate to keep the HIV-1 virus at bay.

PubMed Disclaimer

Comment in

Comment on

  • Influence of HLA-C expression level on HIV control.
    Apps R, Qi Y, Carlson JM, Chen H, Gao X, Thomas R, Yuki Y, Del Prete GQ, Goulder P, Brumme ZL, Brumme CJ, John M, Mallal S, Nelson G, Bosch R, Heckerman D, Stein JL, Soderberg KA, Moody MA, Denny TN, Zeng X, Fang J, Moffett A, Lifson JD, Goedert JJ, Buchbinder S, Kirk GD, Fellay J, McLaren P, Deeks SG, Pereyra F, Walker B, Michael NL, Weintrob A, Wolinsky S, Liao W, Carrington M. Apps R, et al. Science. 2013 Apr 5;340(6128):87-91. doi: 10.1126/science.1232685. Science. 2013. PMID: 23559252 Free PMC article.

Publication types

LinkOut - more resources