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Comment
. 2013 Sep 13;341(6151):1184-5.
doi: 10.1126/science.1243939.

Immunology. Sensing endotoxins from within

Affiliations
Comment

Immunology. Sensing endotoxins from within

Jonathan C Kagan. Science. .
No abstract available

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Sensing lipopolysaccharides
Macrophages respond to Gram-negative bacteria by activating transcriptional and nontranscriptional immune responses. Some of these responses are handled by protein complexes called infl ammasomes. An intracellular sensor for lipopolysaccharides was revealed, but its identity has yet to be determined.

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