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Review
. 2013 Oct;57(4):657-71.
doi: 10.1016/j.cden.2013.07.004. Epub 2013 Aug 15.

An update on granulomatous diseases of the oral tissues

Faizan Alawi  1
Affiliations
Review

An update on granulomatous diseases of the oral tissues

Faizan Alawi. Dent Clin North Am. 2013 Oct.

Abstract

With new insights into the pathogenesis of specific granulomatous diseases, and with the advent of high-throughput genetic screening and availability of next-generation biological therapies, clinicians have several options at their disposal to help ensure accurate diagnosis and effective treatment. This article highlights some of the current knowledge about the more common granulomatous systemic diseases that may be encountered in clinical practice.

Keywords: Biological therapy; Crohn disease; Orofacial granulomatosis; Sarcoidosis; Tuberculosis; Type IV hypersensitivity.

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Figures

Figure 1
Figure 1
Corrugated vestibular mucosa with linear ulceration consistent with Crohn Disease. (Courtesy of Dr. Eric T. Stoopler, Philadelphia, PA.)
Figure 2
Figure 2
Generalized gingival erythema and edema representative of orofacial granulomatosis. (Courtesy of Dr. Eric T. Stoopler, Philadelphia, PA.)
See this image and copyright information in PMC

References

    1. Ramakrishnan L. Revisiting the role of the granuloma in tuberculosis. Nat Rev Immunol. 2012;12:352–366. - PubMed
    1. Alawi F. Granulomatous diseases of the oral tissues: differential diagnosis and update. Dent Clin North Am. 2005;49:203–221. - PubMed
    1. Eveson JW. Granulomatous disorders of the oral mucosa. Semin Diagn Pathol. 1996;13:118–127. - PubMed
    1. Bernath M, Szabo J. Tissue reaction initiated by different sealers. Int Endod J. 2003;36:256–261. - PubMed
    1. Edwards PC, Fantasia JE. Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers. Clin Interv Aging. 2007;2:509–519. - PMC - PubMed

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