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. 1990 Jan;64(1):24-36.
doi: 10.1128/JVI.64.1.24-36.1990.

Nonessential region of bacteriophage P4: DNA sequence, transcription, gene products, and functions

D Ghisotti  1 , S Finkel, C Halling, G Dehò, G Sironi, R Calendar
Affiliations

Nonessential region of bacteriophage P4: DNA sequence, transcription, gene products, and functions

D Ghisotti et al. J Virol. 1990 Jan.

Erratum in

  • J Virol 1990 Apr;64(4):1878

Abstract

We sequenced the leftmost 2,640 base pairs of bacteriophage P4 DNA, thus completing the sequence of the 11,627-base-pair P4 genome. The newly sequenced region encodes three nonessential genes, which are called gop, beta, and cII (in order, from left to right). The gop gene product kills Escherichia coli when the beta protein is absent; the gop and beta genes are transcribed rightward from the same promoter. The cII gene is transcribed leftward to a rho-independent terminator. Mutation of this terminator creates a temperature-sensitive phenotype, presumably owing to a defect in expression of the beta gene.

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References

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