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. 2013 Nov;10(11):1081-2.
doi: 10.1038/nmeth.2642. Epub 2013 Sep 15.

IntOGen-mutations identifies cancer drivers across tumor types

Abel Gonzalez-Perez  1 , Christian Perez-Llamas, Jordi Deu-Pons, David Tamborero, Michael P Schroeder, Alba Jene-Sanz, Alberto Santos, Nuria Lopez-Bigas
Affiliations

IntOGen-mutations identifies cancer drivers across tumor types

Abel Gonzalez-Perez et al. Nat Methods. 2013 Nov.

Abstract

The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making.

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Conflict of interest statement

The authors declare no competing financial interests.

Figures

Figure 1
Figure 1
Schematic representation of the analysis performed by the IntOGen-mutations analysis pipeline.
See this image and copyright information in PMC

References

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