Review
doi: 10.1007/978-1-62703-586-6_4.
Therapeutic human monoclonal antibodies against cancer
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- PMID: 24037836
- DOI: 10.1007/978-1-62703-586-6_4
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Review
Therapeutic human monoclonal antibodies against cancer
Methods Mol Biol.
2014.
Abstract
There are over 30 monoclonal antibodies that are FDA approved for a variety of diseases ranging from malignancies to autoimmune diseases to macular degeneration. These antibodies include murine, fully humanized, and chimeric antibodies. There are a number of monoclonal antibodies used in the treatment of malignancies; in fact, three of the top five grossing antibodies (bevacizumab, trastuzumab, and rituximab) are used in oncology Scolnik (mAbs 1:179-184, 2009).
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