Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Nov-Dec;23(6):637-46.
doi: 10.1038/jes.2013.52. Epub 2013 Sep 18.

Satellite-based PM concentrations and their application to COPD in Cleveland, OH

Affiliations

Satellite-based PM concentrations and their application to COPD in Cleveland, OH

Naresh Kumar et al. J Expo Sci Environ Epidemiol. 2013 Nov-Dec.

Abstract

A hybrid approach is proposed to estimate exposure to fine particulate matter (PM(2.5)) at a given location and time. This approach builds on satellite-based aerosol optical depth (AOD), air pollution data from sparsely distributed Environmental Protection Agency (EPA) sites and local time-space Kriging, an optimal interpolation technique. Given the daily global coverage of AOD data, we can develop daily estimate of air quality at any given location and time. This can assure unprecedented spatial coverage, needed for air quality surveillance and management and epidemiological studies. In this paper, we developed an empirical relationship between the 2 km AOD and PM(2.5) data from EPA sites. Extrapolating this relationship to the study domain resulted in 2.3 million predictions of PM(2.5) between 2000 and 2009 in Cleveland Metropolitan Statistical Area (MSA). We have developed local time-space Kriging to compute exposure at a given location and time using the predicted PM(2.5). Daily estimates of PM(2.5) were developed for Cleveland MSA between 2000 and 2009 at 2.5 km spatial resolution; 1.7 million (∼79.8%) of 2.13 million predictions required for multiyear and geographic domain were robust. In the epidemiological application of the hybrid approach, admissions for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) was examined with respect to time-space lagged PM(2.5) exposure. Our analysis suggests that the risk of AECOPD increases 2.3% with a unit increase in PM(2.5) exposure within 9 days and 0.05° (∼5 km) distance lags. In the aggregated analysis, the exposed groups (who experienced exposure to PM(2.5) >15.4 μg/m(3)) were 54% more likely to be admitted for AECOPD than the reference group. The hybrid approach offers greater spatiotemporal coverage and reliable characterization of ambient concentration than conventional in situ monitoring-based approaches. Thus, this approach can potentially reduce exposure misclassification errors in the conventional air pollution epidemiology studies.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Study area with the location of PM2.5 (particulate matter 2.5) sites, with 2.5 km grid. The inset (right top) of the figure shows that there is just one PM2.5 site in the downtown area and the spacing between two consecutive grid cells.
Figure 2
Figure 2
Predicted (using local time–space Kriging (LTSK)) and observed PM2.5 (particulate matter 2.5, μg/m3) of 2.5% randomly chosen data points in Cleveland Metropolitan Statistical Area (MSA), 2006–2009 (R2~0.84).
Figure 3
Figure 3
PM2.5 (particulate matter 2.5) predicted surface within Cleveland Metropolitan Statistical Area (MSA) across different seasons in 2008.

References

    1. Davidson CI, Phalen R, Solomon P. Airborne particulate matter and human health: a review. Aerosol Sci Technol. 2005;39:737–749.
    1. Jia XF, Song XM, Shima M, Tamura K, Deng FR, Guo XB. Effects of fine particulate on heart rate variability in Beijing: a panel study of healthy elderly subjects. Int Arch Occup Environ Health. 2012;85:97–107. - PubMed
    1. Gualtieri M, Ovrevik J, Mollerup S, Asare N, Longhin E, Dahlman HJ, et al. Airborne urban particles (Milan winter-PM2. 5) cause mitotic arrest and cell death: effects on DNA, mitochondria, AhR binding and spindle organization. Mutat Res. 2011;713:18–31. - PubMed
    1. Murrell RN, Gibson JE. Brevetoxin 2 alters expression of apoptotic, DNA damage, and cytokine genes in Jurkat cells. Hum Exp Toxicol. 2011;30:182–191. - PubMed
    1. Nikasinovic L, Just J, Sahraoui F, Seta N, Grimfeld A, Momas I. Nasal inflammation and personal exposure to fine particles PM2. 5 in asthmatic children. J Allergy Clin Immunol. 2006;117:1382–1388. - PubMed

Publication types

MeSH terms