Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Sep 5:4:582.
doi: 10.3389/fpsyg.2013.00582. eCollection 2013.

The third wave of biological psychiatry

Affiliations

The third wave of biological psychiatry

Henrik Walter. Front Psychol. .

Abstract

In this article I will argue that we are witnessing at this moment the third wave of biological psychiatry. This framework conceptualizes mental disorders as brain disorders of a special kind that requires a multilevel approach ranging from genes to psychosocial mechanisms. In contrast to earlier biological psychiatry approaches, the mental plays a more prominent role in the third wave. This will become apparent by discussing the recent controversy evolving around the recently published DSM-5 and the competing transdiagnostic Research Domain Criteria approach of the National Institute of Mental Health that is build on concepts of cognitive neuroscience. A look at current conceptualizations in biological psychiatry as well as at some discussions in current philosophy of mind on situated cognition, reveals that the thesis, that mental brain disorders are brain disorders has to be qualified with respect to how mental states are constituted and with respect to multilevel explanations of which factors contribute to stable patterns of psychopathological signs and symptoms.

Keywords: DSM-5; RDOC; cognitive neuroscience; genetics; mental disorder; neuroimaging; philosophy of mind; philosophy of psychiatry.

PubMed Disclaimer

References

    1. Buckholtz J. W., Meyer-Lindenberg A. (2012). Psychopathology and the human connectome: toward a transdiagnostic model of risk for mental illness. Neuron 74 990–1004 10.1016/j.neuron.2012.06.002 - DOI - PubMed
    1. Button K. S., Ioannidis J. P. A., Mokrysz C., Nosek B. A., Flint J., Robinson E. S. J., et al. (2012). Power failure: why small sample size undermines the reliability of neuroscience. Nat. Rev. Neurosci. 14 365–376 10.1038/nrn3475 - DOI - PubMed
    1. Clark A., Chalmers D. (1998). The extended mind. Analysis 58 7–19 10.1093/analys/58.1.7 - DOI
    1. Disner S. G., Beevers C., Haigh E. A., Beck A. T. (2011). Neural mechanisms of the cognitive model of depression. Nat. Rev. Neurosci. 12 467–477 10.1038/nrn3027 - DOI - PubMed
    1. Frances A. (2013). Saving Normal: An Insider’s Revolt Against Out-of-Control Psychiatric Diagnosis, -5, Big Pharma, and the Medicalization of Ordinary Life. New York: William Morrow

LinkOut - more resources