[Correlation of splenomegaly and blood picture changes in graft vs host reaction of the mouse]
- PMID: 240470
- DOI: 10.1007/BF01633506
[Correlation of splenomegaly and blood picture changes in graft vs host reaction of the mouse]
Abstract
The early phase of graft-versus-host-reaction is characterized by a rapid decline of lymphocytes in the peripheral blood, with a minimum between days 9 and 11, and return to normal until day 20 after spleen cell grafting. Erythrocytes and hematocrit do not change during this period. There is no causal correlation between splenomegaly and lymphopenia. Lymphopenia provides a criterium for experimental graft-versusu-host-reaction equivalent to the spleen-index.
Similar articles
-
Intraepithelial lymphocyte count and crypt hyperplasia measure the mucosal component of the graft-versus-host reaction in mouse small intestine.Gastroenterology. 1982 Aug;83(2):417-23. Gastroenterology. 1982. PMID: 6979490
-
Changes in spleen cellularity and erythrocyte accumulation following Rauscher virus infection in the mouse.Scand J Haematol. 1973;10(4):273-81. doi: 10.1111/j.1600-0609.1973.tb00072.x. Scand J Haematol. 1973. PMID: 4764609 No abstract available.
-
Graft-versus-host reactions in the beige mouse. An investigation of the role of host and donor natural killer cells in the pathogenesis of graft-versus-host disease.Transplantation. 1987 Aug;44(2):261-7. doi: 10.1097/00007890-198708000-00017. Transplantation. 1987. PMID: 3307050
-
Pathogenesis of graft-versus-host reaction. I. Influence of thymectomy and adrenalectomy on development of lymphopenia.Proc Soc Exp Biol Med. 1972 Mar;139(3):793-8. doi: 10.3181/00379727-139-36239. Proc Soc Exp Biol Med. 1972. PMID: 4401920 No abstract available.
-
[Effect of the graft vs. host reaction on the take and growth of normal and tumorous tissues].Patol Fiziol Eksp Ter. 1973 Jan-Feb;17(1):77-81. Patol Fiziol Eksp Ter. 1973. PMID: 4149834 Review. Russian. No abstract available.
Cited by
-
Effect of generalized graft-versus-host-reaction on B- and T-lymphocytes and a benzpyrene-induced murine sarcoma.Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978 Oct 30;92(3):255-65. doi: 10.1007/BF00461648. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978. PMID: 31740