Design, synthesis and cytotoxic activity evaluation of new aminosubstituted benzofurans
- PMID: 24047215
- DOI: 10.2174/15734064113096660049
Design, synthesis and cytotoxic activity evaluation of new aminosubstituted benzofurans
Abstract
A number of new aminosubstituted benzofuran analogues have been prepared and their cytotoxic/cytostatic activity was investigated against five human tumor cell lines (MCF-7, SKBR3, SKOV3, HCT-116 and HeLa). Certain compounds showed noticeable tumor cell growth inhibition, indicative of possible structure-activity relationships.
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