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. 2013 Oct;19(10):1670-3.
doi: 10.3201/eid1910.130393.

New clonal strain of Candida auris, Delhi, India

Anuradha Chowdhary, Cheshta Sharma, Shalini Duggal, Kshitij Agarwal, Anupam Prakash, Pradeep Kumar Singh, Sarika Jain, Shallu Kathuria, Harbans S Randhawa, Ferry Hagen, Jacques F Meis

New clonal strain of Candida auris, Delhi, India

Anuradha Chowdhary et al. Emerg Infect Dis. 2013 Oct.

Abstract

A new clonal strain of Candida auris is an emerging etiologic agent of fungemia in Delhi, India. In 12 patients in 2 hospitals, it was resistant to fluconazole and genotypically distinct from isolates from South Korea and Japan, as revealed by M13 and amplified fragment length polymorphism typing.

Keywords: AFLP; Candida auris; India; M13 fingerprinting; antifungal susceptibility; fungemia; fungi; parasitic diseases.

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Figures

Figure 1
Figure 1
M13 PCR fingerprinting of Candida auris isolates. Lane 1, marker 50-bp ladder (New England BioLabs, Evry, France); lane 2, C. duobushaemulonii reference isolate (CBS 7798); lanes 3–6, C. auris isolates from South Korea (KCTC 17809 and KCTC 17810), Japan (DSMZ 21092 and JCM 15448), and reference isolates; and lane 7–18, 12 test isolates from India.
Figure 2
Figure 2
Dendrogram of amplified fragment length polymorphism analysis of Candida auris isolates from India, Japan, and South Korea and members of C. haemulonii complex. It was constructed by using UPGMA (unweighted pair group method with averages) in combination with the Pearson correlation coefficient and was restricted to fragments of 60–400 bp. Scale bar indicates the percentage similarity.
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