Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Oct;19(10):1670-3.
doi: 10.3201/eid1910.130393.

New clonal strain of Candida auris, Delhi, India

Anuradha Chowdhary, Cheshta Sharma, Shalini Duggal, Kshitij Agarwal, Anupam Prakash, Pradeep Kumar Singh, Sarika Jain, Shallu Kathuria, Harbans S Randhawa, Ferry Hagen, Jacques F Meis

New clonal strain of Candida auris, Delhi, India

Anuradha Chowdhary et al. Emerg Infect Dis. 2013 Oct.

Abstract

A new clonal strain of Candida auris is an emerging etiologic agent of fungemia in Delhi, India. In 12 patients in 2 hospitals, it was resistant to fluconazole and genotypically distinct from isolates from South Korea and Japan, as revealed by M13 and amplified fragment length polymorphism typing.

Keywords: AFLP; Candida auris; India; M13 fingerprinting; antifungal susceptibility; fungemia; fungi; parasitic diseases.

PubMed Disclaimer

Figures

Figure 1
Figure 1
M13 PCR fingerprinting of Candida auris isolates. Lane 1, marker 50-bp ladder (New England BioLabs, Evry, France); lane 2, C. duobushaemulonii reference isolate (CBS 7798); lanes 3–6, C. auris isolates from South Korea (KCTC 17809 and KCTC 17810), Japan (DSMZ 21092 and JCM 15448), and reference isolates; and lane 7–18, 12 test isolates from India.
Figure 2
Figure 2
Dendrogram of amplified fragment length polymorphism analysis of Candida auris isolates from India, Japan, and South Korea and members of C. haemulonii complex. It was constructed by using UPGMA (unweighted pair group method with averages) in combination with the Pearson correlation coefficient and was restricted to fragments of 60–400 bp. Scale bar indicates the percentage similarity.
See this image and copyright information in PMC

References

    1. Satoh K, Makimura K, Hasumi Y, Nishiyama Y, Uchida K, Yamaguchi H. Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiol Immunol. 2009;53:41–4 . 10.1111/j.1348-0421.2008.00083.x - DOI - PubMed
    1. Kim MN, Shin JH, Sung H, Lee K, Kim EC, Ryoo N, et al. Candida haemulonii and closely related species at 5 university hospitals in Korea: identification, antifungal susceptibility, and clinical features. Clin Infect Dis. 2009;48:e57–61 . 10.1086/597108 - DOI - PubMed
    1. Oh BJ, Shin JH, Kim MN, Sung H, Lee K, Joo MY, et al. Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii, and a proposed new species (Candida auris) isolates from Korea. Med Mycol. 2011;49:98–102 . 10.3109/13693786.2010.493563 - DOI - PubMed
    1. Lee WG, Shin JH, Uh Y, Kang MG, Kim SH, Park KH, et al. First three reported cases of nosocomial fungemia caused by Candida auris. J Clin Microbiol. 2011;49:3139–42 . 10.1128/JCM.00319-11 - DOI - PMC - PubMed
    1. White TJ, Bruns T, Lee S, Taylor J. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. In: Innis MA, Gelfand DH, Sninsky JJ, White TJ, editors. PCR protocols: a guide to methods and applications. San Diego (CA): Academic Press; 1990. p. 315–22.

Publication types

MeSH terms

LinkOut - more resources