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Case Reports
. 2013 Sep 18:2013:bcr2013200909.
doi: 10.1136/bcr-2013-200909.

Giant thoracic mass: an unusual presentation of primary pulmonary Hodgkin's lymphoma

Affiliations
Case Reports

Giant thoracic mass: an unusual presentation of primary pulmonary Hodgkin's lymphoma

Philip James McElnay et al. BMJ Case Rep. .

Abstract

Primary pulmonary Hodgkin's lymphoma (PPHL) is rare. PPHL without peripheral lymphadenopathy or hepatosplenomegaly is exceptionally uncommon. We present a 61-year-old woman believed to have a solitary intrapulmonary fibrous tumour on a CT and a CT-guided biopsy, until surgical excision. Histopathology and immunohistochemistry of the excised mass confirmed PPHL. PPHL is a very rare differential diagnosis of large solitary intrapulmonary masses. A CT-guided biopsy is recommended, as it can be diagnostic, reserving excision for cases where the diagnosis remains in doubt.

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Figures

Figure 1
Figure 1
Initial chest X-ray demonstrating the large mass in the left hemi-thorax.
Figure 2
Figure 2
Preoperative CT chest demonstrating the large mass which occupied almost one-third of the hemi-thorax, and partially compressed the pulmonary artery.
Figure 3
Figure 3
Anterior volumetric rendered CT image showing the mass occupying one-third of the left hemi-thorax.
Figure 4
Figure 4
Anterolateral volumetric rendered CT image of the giant thoracic mass.
Figure 5
Figure 5
Postoperative histology high magnification slide (×400) showing strong CD30 expression (using immunohistochemistry) in the Reed-Sternberg cells.

References

    1. Lluch-Garcia R, Briones-Gomez A, Monzo-Castellano E, et al. Primary pulmonary Hodgkin's lymphoma. Can Respir J 2010;2013:e106–8 - PMC - PubMed
    1. Diederich S, Link TM, Zühlsdorf H, et al. Pulmonary manifestations of Hodgkin's disease: radiographic and CT findings. Eur Radiol 2001;2013:2295–305 - PubMed
    1. Radin AI. Primary pulmonary Hodgkin's disease. Cancer 1990;2013:550–63 - PubMed
    1. Kern WH, Crepeau AG, Jones JC. Primary Hodgkin's disease of the lung. Report of 4 cases and review of the literature. Cancer 1961;2013:1151–65 - PubMed
    1. Kumar R, Sidhu H, Mistry R, et al. Primary pulmonary Hodgkin's lymphoma: a rare pitfall in transthoracic fine needle aspiration cytology. Diagn Cytopathol 2008;2013:666–9 - PubMed

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