Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Sep;23(5):378-80.
doi: 10.4103/0971-4065.116329.

Non-O1, non-O139 Vibrio cholerae sepsis in a patient with nephrotic syndrome

N George  1 , F Fredrick, A Mohapatra, B Veeraraghavan, S T Kakde, A T Valson, G Basu
Affiliations
Case Reports

Non-O1, non-O139 Vibrio cholerae sepsis in a patient with nephrotic syndrome

N George et al. Indian J Nephrol. 2013 Sep.

Abstract

Non-O1, non-O139 Vibrio cholerae is an encapsulated bacterium, ubiquitous in the marine environment and generally considered to be non-pathogenic. However, it is known to cause diarrheal illness, wound infection, and bacteremia in immunocompromised hosts. Here we have describe non-O1, non-O139 V. cholerae sepsis in a patient with nephrotic syndrome following exposure to sea-water. Interestingly, the exposure occurred remotely 4 months prior to the onset of nephrotic syndrome. The occurrence of florid sepsis after a prolonged interval from the time of exposure is peculiar and raises the possibility of an association between occult Vibrio sepsis and nephrotic syndrome.

Keywords: Immunocompromised; nephrotic syndrome; non-O1; non-O139; sepsis; vibrio cholera.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
There is mild increase in mesangial matrix with mesangial hypercellularity, mild thickening of the paramesangial capillary walls with narrowing of capillary lumina. The extraglomerular compartment showed focal mild interstitial fibrosis, focal tubular dilatation with flattening of lining epithelium, hyaline casts, focal infiltrates of lymphocytes and occasional eosinophils
See this image and copyright information in PMC

References

    1. Dalsagaard A, Serichantalergs O, Forslund A, Lin W, Mekalanos J, Mintz E, et al. Clinical and environmental isolates of Vibrio cholerae O141 carry the CTX phage and the genes encoding the toxin-coregulated pili. J Clin Microbiol. 2001;39:4086–92. - PMC - PubMed
    1. Bagchi K, Echeverria P, Arthur JD, Sethabutr O, Serichantalergs O, Hoge WC. Epidemic of diarrhea caused by Vibrio cholerae non-O1 that produced heat stable toxin among Khmers in a camp in Thailand. J Clin Microbiol. 1993;31:1315–7. - PMC - PubMed
    1. Shelton CH, 3rd, Martino RL, Ramsey KM. Recurrent non-O: 1 Vibrio cholerae bacteremia in a patient with multiple myeloma. Cancer. 1993;72:105–7. - PubMed
    1. Petsaris O, Nousbaum JB, Quilici ML, Le Coaudou G, Payan C, Abalain M. Non-O1, non-O139 Vibrio cholerae bacteremia in a cirrhotic patient. J Med Microbiol. 2010;59:1260–2. - PubMed
    1. Dhar R, Badawi M, Qabazard Z, Albert MJ. Vibrio cholerae (non-O1, non-O139) sepsis in a child with Fanconi anemia. Diagn Microbiol Inf Dis. 2004;50:287–9. - PubMed

Publication types