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. 2013 Oct;19(10):1697-9.
doi: 10.3201/eid1910.130946.

Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa

Ndapewa Laudika Ithete, Samantha Stoffberg, Victor Max Corman, Veronika M Cottontail, Leigh Rosanne Richards, M Corrie Schoeman, Christian Drosten, Jan Felix Drexler, Wolfgang Preiser

Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa

Ndapewa Laudika Ithete et al. Emerg Infect Dis. 2013 Oct.
No abstract available

Keywords: Bats; Coronavirus; MERS-CoV; Middle East respiratory syndrome coronavirus; South Africa; viruses; zoonoses.

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Figures

Figure
Figure
Partial RNA-dependent RNA polymerase (RdRp) gene phylogeny, including the novel betacoronavirus from a Neoromicia zuluensis bat in South Africa (GenBank accession no. KC869678 for both partial RdRp and spike gene sequences). The Bayesian phylogeny was done on a translated 816-nt RdRp gene sequence fragment, as described (5). MrBayes V3.1 (http://mrbayes.sourceforge.net/) was used with a WAG substitution model assumption over 2,000,000 generations sampled every 100 steps, resulting in 20,000 trees, of which 25% were discarded as burn-in. A whale gammacoronavirus was used as an outgroup. The novel N. zuluensis bat virus is highlighted in gray. Values at deep nodes represent statistical support from posterior probabilities. Only values >0.9 are shown. Coronavirus clades are depicted to the right of taxa. Scale bar represents genetic distance. MERS-CoV, Middle East respiratory syndrome coronavirus; SARS, severe acute respiratory syndrome; Bt-CoV, bat coronavirus; HCoV, human coronavirus, MHV, mouse hepatitis virus; FCoV, feline coronavirus; TGEV, transmissible gastroenteritis coronavirus.
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