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Review
. 1990 Feb;60(2):61-7.
doi: 10.1007/BF01720509.

Treatment strategies in acute myeloid leukemia (AML). A. First-line chemotherapy

T Buechner  1 , W Hiddemann
Affiliations
Review

Treatment strategies in acute myeloid leukemia (AML). A. First-line chemotherapy

T Buechner et al. Blut. 1990 Feb.

Erratum in

  • Blut 1990 Apr;60(4):259

Abstract

Chemotherapy remains the backbone of treatment in AML. Of all adult patients 65% go into remission and have a chance of longer survival and of even being cured. Among the responders, 25% can be cured by intensive and long-term chemotherapy. Since the effect of chemotherapy appears not to be limited to a special period of time, its antileukemic and curative potential could be further exploited by multiple-step chemotherapy combining double induction, intensified consolidation and long-term maintenance. Improved antimicrobial treatment and the use of hematopoietic growth factors may help making multiple-step chemotherapy practicable, thereby increasing the cure rate in AML.

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