The many sides of CIN

Affiliations

Comment

Kristin A Knouse et al. Nat Rev Mol Cell Biol. 2013 Oct.

. 2013 Oct;14(10):611.

doi: 10.1038/nrm3666.

¹ Koch Institute for Integrative Cancer Biology, Massachusetts Institute of Technology, and Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.

No abstract available

Comment on

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice.
Baker DJ, Jeganathan KB, Cameron JD, Thompson M, Juneja S, Kopecka A, Kumar R, Jenkins RB, de Groen PC, Roche P, van Deursen JM. Baker DJ, et al. Nat Genet. 2004 Jul;36(7):744-9. doi: 10.1038/ng1382. Epub 2004 Jun 20. Nat Genet. 2004. PMID: 15208629
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.
Baker DJ, Dawlaty MM, Wijshake T, Jeganathan KB, Malureanu L, van Ree JH, Crespo-Diaz R, Reyes S, Seaburg L, Shapiro V, Behfar A, Terzic A, van de Sluis B, van Deursen JM. Baker DJ, et al. Nat Cell Biol. 2013 Jan;15(1):96-102. doi: 10.1038/ncb2643. Epub 2012 Dec 16. Nat Cell Biol. 2013. PMID: 23242215 Free PMC article.

1. Baker DJ, et al. BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nature Genetics. 2004;36:744–749. - PubMed
1. Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol. 2007;8:379–393. - PubMed
1. Baker DJ, et al. Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. Nature Cell Biology. 2012;14:1–9. - PMC - PubMed