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Comment
. 2013 Nov;9(11):609-10.
doi: 10.1038/nrneurol.2013.198. Epub 2013 Sep 24.

Neuro-oncology: The long and winding road--gene therapy for glioma

Maria G Castro  1 , Pedro R Lowenstein
Affiliations
Comment

Neuro-oncology: The long and winding road--gene therapy for glioma

Maria G Castro et al. Nat Rev Neurol. 2013 Nov.

Abstract

Gene therapy approaches for glioblastoma multiforme (GBM) have been under investigation in clinical trials since the 1990s, but the results to date have been disappointing. A recently published phase III trial of adenovirus-based gene therapy for GBM has demonstrated modest—but possibly clinically relevant—improvements in patient survival.

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Conflict of interest statement

Competing interests

The authors declare no competing interests.

Comment on

References

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