Importance of spinal deformity index in risk evaluation of VCF (vertebral compression fractures) in obese subjects: prospective study
- PMID: 24061969
- PMCID: PMC3830052
- DOI: 10.1007/s00586-013-3009-9
Importance of spinal deformity index in risk evaluation of VCF (vertebral compression fractures) in obese subjects: prospective study
Erratum in
- Eur Spine J. 2013 Nov;22 Suppl 6:S950. Rossi, D [removed]; Rubino, M [added]
Abstract
Introduction: Obesity and osteoporosis share many features and recent studies have identified many similarities suggesting common pathophysiological mechanisms. Obesity is associated with a higher risk of non-traumatic fractures despite bone mineral density (BMD) being normal or even increased.
Materials and methods: 54 obese subjects were analyzed (51 ± 16 years, 10 males, 44 females). Spinal deformity index (SDI) is a semi-quantitative method that may be a surrogate index of bone microarchitecture. SDI index was higher in patients than in controls. In 87.5 % of patients and 10 % of controls we found morphometric vertebral fractures, despite a DEXA Tscore not diagnostic of osteoporosis.
Conclusion: The objective of this study was to assess in obese patients levels of 25OH vitamin D, parathyroid hormone, serum and urinary calcium (Ca) and phosphorus (P), BMD, and SDI. 87.5 % of the obese subjects present nontraumatic vertebral fractures and reduced bone quality as measured by SDI.
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