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. 2012 Apr;1(1):75-8.
doi: 10.1177/2048872612441580.

A strategy for addressing aspirin hypersensitivity in patients requiring urgent PCI

Affiliations

A strategy for addressing aspirin hypersensitivity in patients requiring urgent PCI

Patrick Schiano et al. Eur Heart J Acute Cardiovasc Care. 2012 Apr.

Abstract

Aspirin is key to the treatment of acute myocardial infarction, particularly if stent implantation is considered. In patients with a history of hypersensitivity to aspirin, the optimal management of ST-segment elevation acute myocardial infarction is unclear. We suggest a strategy for addressing this problem by performing percutaneous coronary intervention with antiplatelet therapy by intravenous glycoprotein IIb/IIIa receptor blockers and performing rapid oral desensitization in the ensuing hours, once the patient has stabilized.

Keywords: Acute myocardial infarction; allergy; aspirin; desensitisation.

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Figures

Figure 1.
Figure 1.
ECG at admission with persistent ST-segment elevation in the inferior’s leads
Figure 2
Figure 2
Posterior descending artery occlusion and right coronary stenosis (segment II)
Figure 3.
Figure 3.
Post-PCI, with final TIMI flow 3 in the right coronary artery

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