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. 2013:2013:723583.
doi: 10.1155/2013/723583. Epub 2013 Aug 26.

Gorham's Disease of the Mandible

Rathy Ravindran  1 , Anila Karunakaran
Affiliations

Gorham's Disease of the Mandible

Rathy Ravindran et al. Case Rep Dent. 2013.

Abstract

Gorham's disease is a rare condition characterized by progressive osteolysis of bone with ultimate total disappearance of bone. The aetiology is undetermined. It may affect any bone of the body, although there is predilection for the pelvis, humerus, axial skeleton, and mandible. Because of the rarity, the disorder goes unrecognized. Various treatment modalities are undertaken with very limited success. We report a case of Gorham's disease of mandible in a 62-year-old man and the literature is reviewed with emphasis on aetiology, diagnosis management.

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Figures

Figure 1
Figure 1
Extraoral examination revealed mild diffuse swelling of left lower face.
Figure 2
Figure 2
Intraoral examination revealed missing molars.
Figure 3
Figure 3
Orthopantomogram (OPG) revealed ill-defined osteolytic region involving body and ascending ramus of mandible.
Figure 4
Figure 4
Follow-up OPG taken after 3 months revealed osteolysis extending to involve condyle.
Figure 5
Figure 5
Fibrous connective tissue showing numerous thin walled vascular spaces (H&E 10x).
See this image and copyright information in PMC

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