Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Sep 25:11:241.
doi: 10.1186/1477-7819-11-241.

A popliteal giant synovial osteochondroma mimicking a parosteal osteosarcoma

Affiliations
Case Reports

A popliteal giant synovial osteochondroma mimicking a parosteal osteosarcoma

Andreas Toepfer et al. World J Surg Oncol. .

Abstract

Both giant synovial osteochondroma and parosteal osteosarcoma are rare musculo-skeletal tumors, often localized in the vicinity of the knee. Misdiagnosis of a malignant bone tumor can entail fatal consequences. Etiology of giant synovial osteochondroma is widely unsolved but is believed to originate from synovial chondromatosis, a mostly benign metaplasia of the synovial membrane. Parosteal osteosarcoma is a low-grade surface osteosarcoma with a propensity of local recurrence and the potential of distant metastasis and therefore requiring a different therapeutical approach. We report the case of a popliteal giant osteochondroma mimicking a parosteal osteosarcoma. Relevant facts of this rare entity regarding pathogenesis, treatment, and differential diagnoses will be discussed.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Anterior-posterior plain radiograph of the lesion.
Figure 2
Figure 2
Lateral plain radiograph of the lesion.
Figure 3
Figure 3
T1-weighted (A) and T2-weighted (B) sagittal MR image of the lesion (arrow).
Figure 4
Figure 4
T1-weighted SPIR sequence, transversal cross-sectioning with gadolinium contrast medium enhancement.
Figure 5
Figure 5
Whole-body bone scintigraphy.
Figure 6
Figure 6
Macroscopic specimen after excisional biopsy.
Figure 7
Figure 7
Sawcuts of the lesion and the attached tendon-like soft tissue nodule (arrows).
Figure 8
Figure 8
Second specimen, EVG-staining, 2.5× microscopic magnification.
Figure 9
Figure 9
EVG-staining, 16× microscopic magnification of the hyalinous cap of the primary lesion.
Figure 10
Figure 10
Exemplary lateral radiograph of a parosteal osteosarcoma, loco typico.

References

    1. Fletcher C, Unni K, Mertens F. World health organization classification of tumours: pathology and genetics of tumours of soft tissue and bone. Malignant fibrous histiocytoma of bone. Lyon: IARC Press; 2002.
    1. Grimer R. WHO Classification of Tumours of Soft Tissue and Bone, Volume 5. 4. Geneva: WHO Press; 2013.
    1. Freyschmidt JOH, Jundt G. Knochenutmoren mit kiefertumoren: klinik-radiologie-pathologie. Berlin: Springer; 2010.
    1. Cohen AP, Giannoudis PV, Hinsche A, Smith RM, Matthews SJ. Post-traumatic giant intraarticular synovial osteochondroma of the knee. Injury. 2001;32:87–89. doi: 10.1016/S0020-1383(00)00090-5. - DOI - PubMed
    1. Mosher JF Jr, Kettelkamp DB, Campbell CJ. Intracapsular or para-articular chondroma. A report of three cases. J Bone Joint Surg Am. 1966;48:1561–1569. - PubMed

Publication types