Interpreting patient treatment response in analgesic clinical trials: implications for genotyping, phenotyping, and personalized pain treatment

Affiliations

¹ Departments of Anesthesiology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Departments of Biostatistics and Computational Biology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Department of Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Competence Center for Methodology and Statistics, CRP Santé, Strassen, Luxembourg.

Review

Robert H Dworkin et al. Pain. 2014 Mar.

. 2014 Mar;155(3):457-460.

doi: 10.1016/j.pain.2013.09.019. Epub 2013 Sep 23.

¹ Departments of Anesthesiology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Departments of Biostatistics and Computational Biology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Department of Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Competence Center for Methodology and Statistics, CRP Santé, Strassen, Luxembourg.

No abstract available

Keywords: Genotyping; Mechanism-based treatment; Phenotyping; Treatment response; Treatment-by-patient interaction.

References

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