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Case Reports
. 2013 Sep 10;5(3):206-8.
doi: 10.4274/Jcrpe.1037.

Neonatal seizure as a manifestation of unrecognized maternal hyperparathyroidism

Hüseyin Anıl Korkmaz  1 , Behzat Ozkan, Demet Terek, Ceyhun Dizdarer, Sertaç Arslanoğlu
Affiliations
Case Reports

Neonatal seizure as a manifestation of unrecognized maternal hyperparathyroidism

Hüseyin Anıl Korkmaz et al. J Clin Res Pediatr Endocrinol. .

Abstract

Maternal hypercalcemia suppresses parathyroid activity in the fetus resulting in impaired parathyroid responsiveness to hypocalcemia after birth. Resultant hypocalcemia may be severe and prolonged and rarely may lead to convulsions. Here, we present a newborn infant admitted to the pediatric emergency department at age two weeks with recurrent tonic convulsions due to asymptomatic maternal hyperparathyroidism and vitamin D deficiency. Physicians should be aware that undiagnosed maternal hyperparathyroidism can cause severe hypocalcemia in the newborn.

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