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Review
. 2013:9:1393-409.
doi: 10.2147/NDT.S45931. Epub 2013 Sep 16.

Saccadic eye movement applications for psychiatric disorders

Juliana Bittencourt  1 , Bruna Velasques, Silmar Teixeira, Luis F Basile, José Inácio Salles, Antonio Egídio Nardi, Henning Budde, Mauricio Cagy, Roberto Piedade, Pedro Ribeiro
Affiliations
Review

Saccadic eye movement applications for psychiatric disorders

Juliana Bittencourt et al. Neuropsychiatr Dis Treat. 2013.

Abstract

Objective: The study presented here analyzed the patterns of relationship between oculomotor performance and psychopathology, focusing on depression, bipolar disorder, schizophrenia, attention-deficit hyperactivity disorder, and anxiety disorder.

Methods: Scientific articles published from 1967 to 2013 in the PubMed/Medline, ISI Web of Knowledge, Cochrane, and SciELO databases were reviewed.

Results: Saccadic eye movement appears to be heavily involved in psychiatric diseases covered in this review via a direct mechanism. The changes seen in the execution of eye movement tasks in patients with psychopathologies of various studies confirm that eye movement is associated with the cognitive and motor system.

Conclusion: Saccadic eye movement changes appear to be heavily involved in the psychiatric disorders covered in this review and may be considered a possible marker of some disorders. The few existing studies that approach the topic demonstrate a need to improve the experimental paradigms, as well as the methods of analysis. Most of them report behavioral variables (latency/reaction time), though electrophysiological measures are absent.

Keywords: anxiety disorder; attention-deficit hyperactivity disorder; bipolar disorder; depression; schizophrenia.

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References

    1. Bremmer F, Kubischick M, Hoffman K, Krekelberg B. Neural dynamics of saccadic suppression. J Neurosci. 2009;29(40):12374–12383. - PMC - PubMed
    1. Jagla F, Jergelová M, Riecanský I. Saccadic eye movement related potentials. Physiol Res. 2007;56(6):707–713. - PubMed
    1. Findlay JM, Blythe HI. Saccade target selection: Do distractors affect saccade accuracy? Vision Res. 2009;49(10):1267–1274. - PubMed
    1. Thurtell MJ, Tomsak RL, Leigh RJ. Disorders of Saccades. Curr Neurol Neurosci Rep. 2007;7(5):407–416. - PubMed
    1. Fukushima J, Fukushima K, Chiba T, Tanaka S, Yamashita I, Kato M. Disturbances of voluntary control of saccadic eye movements in schizophrenic patients. Biol Psychiatry. 1988;23(7):670–677. - PubMed

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