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Case Reports
. 2013 Dec;82(3):506-8.
doi: 10.1016/j.lungcan.2013.08.030. Epub 2013 Sep 8.

Primary non-small cell lung cancer response upon treatment with denosumab

A Curioni-Fontecedro  1 , L Husmann, D Soldini, R A Stahel
Affiliations
Case Reports

Primary non-small cell lung cancer response upon treatment with denosumab

A Curioni-Fontecedro et al. Lung Cancer. 2013 Dec.

Abstract

Here we report the case of a patient with metastatic adenocarcinoma of the lung harboring an ALK gene translocation. In this patient a response of the primary tumor and metastases has been detected upon treatment with denosumab. A possible link between ALK and RANK is postulated.

Keywords: ALK; Crizotinib; Denosumab; NF-kB; Non small cell lung cancer; RANK; RANKL.

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