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. 1990 Mar;58(3):761-5.
doi: 10.1128/iai.58.3.761-765.1990.

Protein phosphorylation by protein kinase C in HEp-2 cells infected with enteropathogenic Escherichia coli

T J Baldwin  1 , S F Brooks, S Knutton, H A Manjarrez Hernandez, A Aitken, P H Williams
Affiliations

Protein phosphorylation by protein kinase C in HEp-2 cells infected with enteropathogenic Escherichia coli

T J Baldwin et al. Infect Immun. 1990 Mar.

Erratum in

  • Infect Immun 1990 Jun;58(6):2024

Abstract

Infection of HEp-2 monolayers with enteropathogenic Escherichia coli 2036-80 (O119) stimulated phosphorylation of several target cell proteins, the most prominent of which had apparent molecular weights of 21,000 and 29,000. Proteins of the same size were phosphorylated in response to known activators of the calcium-phospholipid-dependent protein kinase C. Screening of clinical isolates of various O serogroups revealed that all strains able to form the characteristic attaching and effacing lesion of enteropathogenic E. coli showed elevated phosphorylation of 21,000- and 29,000-dalton protein species.

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References

    1. Infect Immun. 1989 Apr;57(4):1290-8 - PubMed
    1. FASEB J. 1988 Aug;2(11):2670-6 - PubMed
    1. J Cell Sci. 1988 Aug;90 ( Pt 4):645-55 - PubMed
    1. J Cell Sci. 1988 Aug;90 ( Pt 4):657-66 - PubMed
    1. FEBS Lett. 1989 Jul 3;250(2):362-6 - PubMed