Magnetic resonance imaging and ultrasound evaluation after breast autologous fat grafting combined with platelet-rich plasma

Abstract

Background: Breast lipofilling is a fairly simple and safe procedure if it is performed by experienced surgeons.

Methods: The authors evaluated the radiologic findings from 24 breasts (15 women) subjected to a lipofilling procedure (two sessions) for corrective surgery or cosmetic reasons. Mammography, ultrasound, and magnetic resonance imaging were performed before the first lipofilling session (T0) and 12 months after the last session (T12); ultrasound and magnetic resonance imaging were used 3 months after the first session (Ti) and 3 and 6 months after the last session (T3 and T6). Volumetric evaluations were also made through three-dimensional magnetic resonance imaging reconstruction.

Results: Ultrasound showed oily cysts in 66.67 percent of the breasts at Ti, 70.83 percent at T3, 62.5 percent at T6, and 45.83 percent at T12, whereas magnetic resonance imaging detected oily cysts in 8.33 percent at Ti and T3 and T6 months and 4.17 percent at T12. At Ti, T3, and T6, the cytosteatonecrotic areas identified on both ultrasound and magnetic resonance imaging were unchanged (8.33 percent), whereas at T12 those cytosteatonecrotic areas were increased on ultrasound (12.5 percent) and even more on the magnetic resonance imaging scans (16.67 percent). The average resorption percentage of injected volume was 15.36 percent at T6 months and 28.23 percent at T12 months.

Conclusions: Postlipofilling breast changes can be distinguished from malignant alterations by experienced radiologists and need not interfere with early cancer diagnosis if patients are checked regularly. Moreover, magnetic resonance imaging is very useful for breast volume assessments and for detecting possible changes during longitudinal study.

Clinical question/level of evidence: Therapeutic, IV.