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. 2014 Jan-Feb;39(1):55-64.
doi: 10.1093/jpepsy/jst073. Epub 2013 Sep 26.

Correlates of health-related quality of life in pediatric inflammatory bowel disease: a cumulative risk model approach

Amitha Prasad Gumidyala  1 , Rachel Neff Greenley
Affiliations

Correlates of health-related quality of life in pediatric inflammatory bowel disease: a cumulative risk model approach

Amitha Prasad Gumidyala et al. J Pediatr Psychol. 2014 Jan-Feb.

Abstract

Objective: To examine associations between disease-related, individual, and contextual risk factors and health-related quality of life (HRQoL) in a sample of youth with inflammatory bowel disease using a cumulative risk model framework.

Methods: Participants were 50 youth (58% male; M age = 15 years). Youth and parents completed measures of HRQoL, psychological functioning, and family functioning. Disease information was collected from medical record reviews. Medication adherence was electronically monitored via MEMS cap bottles. A cumulative risk index (CRI) was constructed based on disease activity, disease type, gender, anxiety/depression, medication adherence, general family functioning, disease-specific family functioning, and socioeconomic status.

Results: The CRI was associated with all youth- and mother-reported HRQoL domains. Furthermore, contextual domain factors were most consistently associated with youth and maternal reports of HRQoL.

Conclusion: These results show promise in supporting the value of the CRI in identifying potential risk factors for lower HRQoL in a cross-sectional sample.

Keywords: adolescents; inflammatory bowel disease; quality of life.

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