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. 2013 Dec;57(12):6389-92.
doi: 10.1128/AAC.01509-13. Epub 2013 Sep 30.

In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria

Y López  1 , M Tato, P Espinal, F Garcia-Alonso, D Gargallo-Viola, R Cantón, J Vila
Affiliations

In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria

Y López et al. Antimicrob Agents Chemother. 2013 Dec.

Abstract

In vitro activity of ozenoxacin, a novel nonfluorinated topical (L. D. Saravolatz and J. Leggett, Clin. Infect. Dis. 37:1210-1215, 2003) quinolone, was compared with the activities of other quinolones against well-characterized quinolone-susceptible and quinolone-resistant Gram-positive bacteria. Ozenoxacin was 3-fold to 321-fold more active than other quinolones. Ozenoxacin could represent a first-in-class nonfluorinated quinolone for the topical treatment of a broad range of dermatological infections.

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Figures

Fig 1
Fig 1
Structure of ozenoxacin.
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