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. 2013 Jul;4(2):316-20.
doi: 10.4103/0976-9668.116988.

The role of stroma in the expansion of odontogenic cysts and adenomatoid odontogenic tumor: A polarized microscopy study

Aarti M Mahajan  1 , Mahendra C Mahajan, S M Ganvir, V K Hazarey
Affiliations

The role of stroma in the expansion of odontogenic cysts and adenomatoid odontogenic tumor: A polarized microscopy study

Aarti M Mahajan et al. J Nat Sci Biol Med. 2013 Jul.

Abstract

Objectives: To compare the polarization colors of collagen fibers of odontogenic keratocyst (OKC), radicular cyst, dentigerous cyst, and adenomatoid odontogenic tumor (AOT) with reference to their biological behavior.

Study design: Twenty cases each of OKC, radicular cyst, dentigerous cyst, and AOT were stained with picrosirius red stain and studied under polarized light.

Results: A predominance of green to greenish yellow thick fibers was noted in OKC and AOT as compared to dentigerous cyst and radicular cyst. There was no significant difference between the polarization colors of the thin fibers in all the three groups.

Conclusion: The stroma of OKC and AOT consists of poorly packed or pathologic collagen and plays a role in its neoplastic behavior.

Keywords: Adenomatoid odontogenic tumor; collagen; odontogenic keratocyst; polarized microscopy.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Picrosirius red-stained section of adenomatoid tumor showing a predominance of greenish yellow thick fibers
Figure 2
Figure 2
Picrosirius red-stained section of odontogenic keratocyst showing a predominance of greenish yellow thick fibers
Figure 3
Figure 3
Picrosirius red-stained section of dentigerous cyst showing a predominance of orange red thick fibers
Figure 4
Figure 4
Picrosirius red-stained section of radicular cyst showing a predominance of yellow red to orange red thick fibers
See this image and copyright information in PMC

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