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. 1985 Apr;45(2):165-8.
doi: 10.3109/00365518509160990.

Platelet alpha granule release in diabetes mellitus

S Sacchi, G Curci, L Piccinini, F Cucci, A Messerotti, R Roncaia, P G Benedetti

Platelet alpha granule release in diabetes mellitus

S Sacchi et al. Scand J Clin Lab Invest. 1985 Apr.

Abstract

We studied beta-thromboglobulin (BTG) and platelet factor 4 (PF4) plasma levels in 90 diabetic subjects; we found high plasma values of these proteins only in patients with complications. To provide further indications regarding the role of platelet activation in the pathogenesis of diabetic microangiopathy, we also tested mobilizable platelet content of BTG and PF4; we found these similar to those of normal subjects.

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