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Case Reports
. 2013 Sep;17(5):922-3.
doi: 10.4103/2230-8210.117220.

Acute mania after thyroxin supplementation in hypothyroid state

Rohit Verma  1 , Ankur Sachdeva, Yogendra Singh, Yatan P S Balhara
Affiliations
Case Reports

Acute mania after thyroxin supplementation in hypothyroid state

Rohit Verma et al. Indian J Endocrinol Metab. 2013 Sep.

Abstract

The current literature variedly ascribes depressive and manic symptoms to hypo- and hyperthyroid state, respectively, reporting mania in hypothyroidism as an unusual entity. More unusual is precipitation of manic state in hypothyroid subjects after thyroxine supplementation for which studies report otherwise treating manic symptoms in hypothyroid state with thyroxine. We report a case of a patient whose acute mania appears to have been precipitated by thyroxine supplementation in hypothyroidism state. This case underscores the importance of thyroid screening in patients with mood and psychotic disorders, as well as the potency of thyroxine in producing manic symptoms.

Keywords: Hypothroidism; mania; thyroxine supplementation.

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Conflict of interest statement

Conflict of Interest: None declared

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