Next-generation sequencing for clinical diagnostics

Affiliations

Editorial

Howard J Jacob. N Engl J Med. 2013.

. 2013 Oct 17;369(16):1557-8.

doi: 10.1056/NEJMe1310846. Epub 2013 Oct 2.

¹ From the Departments of Physiology and Pediatrics, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee.

No abstract available

Comment in

Genetic diagnosis through whole-exome sequencing.
Rosen JM. Rosen JM. N Engl J Med. 2014 Mar 13;370(11):1068. doi: 10.1056/NEJMc1315908. N Engl J Med. 2014. PMID: 24620875 No abstract available.
Genetic diagnosis through whole-exome sequencing.
Jacob HJ. Jacob HJ. N Engl J Med. 2014 Mar 13;370(11):1069. doi: 10.1056/NEJMc1315908. N Engl J Med. 2014. PMID: 24627900 No abstract available.

Clinical whole-exome sequencing for the diagnosis of mendelian disorders.
Yang Y, Muzny DM, Reid JG, Bainbridge MN, Willis A, Ward PA, Braxton A, Beuten J, Xia F, Niu Z, Hardison M, Person R, Bekheirnia MR, Leduc MS, Kirby A, Pham P, Scull J, Wang M, Ding Y, Plon SE, Lupski JR, Beaudet AL, Gibbs RA, Eng CM. Yang Y, et al. N Engl J Med. 2013 Oct 17;369(16):1502-11. doi: 10.1056/NEJMoa1306555. Epub 2013 Oct 2. N Engl J Med. 2013. PMID: 24088041 Free PMC article.