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. 1985;77(1-2):155-7.
doi: 10.1159/000233771.

Naturally occurring flavonoids and human basophil histamine release

Naturally occurring flavonoids and human basophil histamine release

E Middleton Jr et al. Int Arch Allergy Appl Immunol. 1985.

Abstract

Naturally occurring plant flavonoids, normal dietary constituents, affect a variety of cell activation phenomena including the secretion of histamine from human basophils stimulated by a variety of agents (antigen, anti-IgE, concanavalin A, ionophore A23187, formyl-Met-Leu-Phe and tetradecanoyl phorbol acetate). Variable profiles of inhibition are seen depending on the nature of the stimulus and the chemical structure of flavonoids.

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