Your gut is right to turn left
- PMID: 24091006
- PMCID: PMC3888821
- DOI: 10.1016/j.devcel.2013.08.018
Your gut is right to turn left
Abstract
Transcriptional factor Pitx2 is a key regulator of left-right asymmetry in the developing gut. In this issue of Developmental Cell, Welsh et al. (2013) identify the formin Daam2, an effector of Wnt signaling, as a key cellular target of Pitx2 required for morphogenetic events during asymmetric gut formation.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Integration of left-right Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2.Dev Cell. 2013 Sep 30;26(6):629-44. doi: 10.1016/j.devcel.2013.07.019. Dev Cell. 2013. PMID: 24091014 Free PMC article.
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