Rapamycin prolongs female reproductive lifespan
- PMID: 24091532
- PMCID: PMC3895422
- DOI: 10.4161/cc.26578
Rapamycin prolongs female reproductive lifespan
Keywords: female rats; female reproductive lifespan; mTOR signaling; ovarian follicle development; primordial follicle activation; rapamycin; sirtuins.
Comment on
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Rapamycin preserves the follicle pool reserve and prolongs the ovarian lifespan of female rats via modulating mTOR activation and sirtuin expression.Gene. 2013 Jul 1;523(1):82-7. doi: 10.1016/j.gene.2013.03.039. Epub 2013 Apr 6. Gene. 2013. PMID: 23566837
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