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Review
. 2013 Oct;27(5):1021-48.
doi: 10.1016/j.hoc.2013.07.012. Epub 2013 Aug 26.

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma

Jolieke G van Oosterwijk  1 , Jakob K Anninga, Hans Gelderblom, Anne-Marie Cleton-Jansen, Judith V M G Bovée
Affiliations
Review

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma

Jolieke G van Oosterwijk et al. Hematol Oncol Clin North Am. 2013 Oct.

Abstract

Osteosarcoma and chondrosarcoma are the 2 most common malignant bone tumors. This review discusses the clinicopathologic features, recent preclinical developments, and targets currently being or to be validated in the clinic.

Keywords: Bone tumor; Chemotherapy; Chondrosarcoma; Hypoxia; Osteosarcoma; Sarcoma; Targeted therapy.

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