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Review
. 2013 Oct;48(5):358-63.
doi: 10.1016/j.jcjo.2013.03.021. Epub 2013 Sep 2.

Fundus-driven perimetry (microperimetry) compared to conventional static automated perimetry: similarities, differences, and clinical applications

Affiliations
Review

Fundus-driven perimetry (microperimetry) compared to conventional static automated perimetry: similarities, differences, and clinical applications

Jennifer H Acton et al. Can J Ophthalmol. 2013 Oct.

Abstract

Fundus-driven perimetry, commonly known as microperimetry, is a technique for measuring visual field sensitivity, whilst simultaneously viewing the fundus. In this article, we review the technique, focusing on the MP-1 microperimeter (Nidek Instruments, Inc, Padua, Italy); we compare it with conventional static automated perimetry, emphasizing the importance of understanding the effects of the different stimulus conditions and data analyses on the interpretation of microperimetry data. The clinical applications of the technique, in the evaluation of functional and structural changes that accompany retinal diseases, are illustrated by its use in patients with age-related macular degeneration, Stargardt disease, and retinitis pigmentosa. In addition, the advantages and limitations of the technique are summarized.

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Figures

Figure 1
Figure 1
(Top) Humphrey Field Analyzer (10-2 pattern, SITA Standard) and (bottom) MP-1 microperimetry (10-2 pattern, 4-2 strategy) results from a normal individual (age 29).
Figure 2
Figure 2
(Left) Segmented SD-OCT image from an eye with early AMD. A computer-aided manual segmentation procedure was used. The following layers have been demarcated (from outer to inner retina): Bruch’s membrane (red), retinal pigment epithelium (lower border: yellow and upper border: green) and inner segment ellipsoid band (blue). (Right) MP-1 microperimetry 10-2 visual field superimposed on a colour fundus photo. The white line corresponds to the SD-OCT scan.
Figure 3
Figure 3
MP-1 microperimetry 10-2 results for 2 patients with retinitis pigmentosa superimposed on short-wavelength fundus autofluorescent images.

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