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. 2013 Oct 3;13(4):377-8.
doi: 10.1016/j.stem.2013.09.010.

Build-a-brain

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Build-a-brain

Stuart M Chambers et al. Cell Stem Cell. .
Free article

Abstract

A major barrier in understanding nervous system development is modeling the cellular interactions that form the human brain. Recently, in the journal Nature, Lancaster et al. (2013) established a protocol for culturing pluripotent stem cell (PSC)-derived "cerebral organoids" that mimics the developing human brain's cellular organization, segregates into distinct brain regions, and models microcephaly.

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