Build-a-brain
- PMID: 24094317
- DOI: 10.1016/j.stem.2013.09.010
Build-a-brain
Abstract
A major barrier in understanding nervous system development is modeling the cellular interactions that form the human brain. Recently, in the journal Nature, Lancaster et al. (2013) established a protocol for culturing pluripotent stem cell (PSC)-derived "cerebral organoids" that mimics the developing human brain's cellular organization, segregates into distinct brain regions, and models microcephaly.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Cerebral organoids model human brain development and microcephaly.Nature. 2013 Sep 19;501(7467):373-9. doi: 10.1038/nature12517. Epub 2013 Aug 28. Nature. 2013. PMID: 23995685 Free PMC article.
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