The effects of adenosine and of some adenosine analogues on the concanavalin A-or acetylcholine-induced histamine release from human adenoidal mast cells
- PMID: 2409762
- DOI: 10.1007/BF01983122
The effects of adenosine and of some adenosine analogues on the concanavalin A-or acetylcholine-induced histamine release from human adenoidal mast cells
Abstract
Histamine release induced by concanavalin A (Con A) or acetylcholine is enhanced by adenosine or the adenosine analogues PIA and NECA. The enhancement is not affected by preincubation with adenosine deaminase. The degree of the Con A-induced histamine release decreases with increasing incubation time. Under these conditions, the enhancing effect of adenosine on histamine release is either abolished or even reversed to inhibition.
References
MeSH terms
Substances
LinkOut - more resources
Research Materials