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Review
. 2013;9(10):e1003552.
doi: 10.1371/journal.ppat.1003552. Epub 2013 Oct 3.

Feeding uninvited guests: mTOR and AMPK set the table for intracellular pathogens

Jason Brunton  1 , Shaun Steele, Benjamin Ziehr, Nathaniel Moorman, Thomas Kawula
Affiliations
Review

Feeding uninvited guests: mTOR and AMPK set the table for intracellular pathogens

Jason Brunton et al. PLoS Pathog. 2013.
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Infection by diverse pathogens impacts AMPK and mTOR signaling.
Several intracellular pathogens manipulate the AMPK/mTOR pathway during infection through either directly targeting AMPK or mTOR or by targeting the upstream or downstream pathways. Depicted here are specific points of manipulation in the mTOR/AMPK pathway by human cytomegalovirus (HCMV), hepatitis C virus (HCV), Rift Valley fever virus (RVFV), simian virus 40 (SV40), Leishmania, and Francisella species. The table summarizes the resulting effects on the activities of mTOR and AMPK from infection by the specific pathogen.
See this image and copyright information in PMC

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