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Case Reports
. 1985 Aug;57(8):811-3.
doi: 10.1093/bja/57.8.811.

Probable histamine liberation with atracurium. A case report

G G Lavery, M M Boyle, R K Mirakhur
Free article
Case Reports

Probable histamine liberation with atracurium. A case report

G G Lavery et al. Br J Anaesth. 1985 Aug.
Free article

Abstract

An histaminoid reaction after the administration of thiopentone and atracurium is described. Serial blood sampling showed no evidence of complement activation. Intradermal testing 6 weeks later yielded a positive result with atracurium (1 in 1000), but not with thiopentone. The clinical course of the reaction and the subsequent investigations suggest a direct pharmacological liberation of histamine.

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