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. 1985 Aug;66(2):439-43.

In vitro culture of leukemic cells in t(4;11) acute leukemia

R C Stong, J H Kersey
  • PMID: 2410069
Free article

In vitro culture of leukemic cells in t(4;11) acute leukemia

R C Stong et al. Blood. 1985 Aug.
Free article

Abstract

In the present study we utilized a semisolid culture system with feeder cells and enriched media to evaluate the growth of acute leukemia associated with the 4;11 chromosomal translocation. We compared growth of t(4;11) leukemia to typical acute nonlymphocytic leukemia (ANL) and acute lymphocytic leukemia (ALL). The two cases of t(4;11) leukemia tested exhibited the highest cloning efficiency of cells tested. The growth characteristics of t(4;11) leukemia were more similar to ANL than ALL.

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