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Comment
. 2013 Dec;10(12):683-4.
doi: 10.1038/nrcardio.2013.157. Epub 2013 Oct 8.

Prevention: Polypills for cardiovascular prevention: a step forward?

Ginés Sanz  1 , Valentin Fuster
Affiliations
Comment

Prevention: Polypills for cardiovascular prevention: a step forward?

Ginés Sanz et al. Nat Rev Cardiol. 2013 Dec.

Abstract

The effect of a fixed-dose combination drug strategy ('polypill') on patients' adherence to medication was analysed in a series of 2,004 individuals with, or at high risk of, cardiovascular disease in the UMPIRE study. The polypill improved adherence by >20%, but the reduction in blood-pressure and cholesterol levels was modest.

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