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Review
. 2013 Sep;5 Suppl 4(Suppl 4):S389-96.
doi: 10.3978/j.issn.2072-1439.2013.07.10.

Treatment of non-small cell lung cancer (NSCLC)

Konstantinos Zarogoulidis  1 , Paul Zarogoulidis, Kaid Darwiche, Efimia Boutsikou, Nikolaos Machairiotis, Kosmas Tsakiridis, Nikolaos Katsikogiannis, Ioanna Kougioumtzi, Ilias Karapantzos, Haidong Huang, Dionysios Spyratos
Affiliations
Review

Treatment of non-small cell lung cancer (NSCLC)

Konstantinos Zarogoulidis et al. J Thorac Dis. 2013 Sep.

Abstract

Radical surgery is the standard of care for fit stage I non-small cell lung cancer (NSCLC) patients. Adjuvant treatment should be offered only as part of an investigation trial. Stage II and IIIA adjuvant cisplatin-based chemotherapy remains the gold standard for completely resected NSCLC tumors. Additionally radiotherapy should be offered in patients with N2 lymph nodes. In advanced stage IIIB/IV or inoperable NSCLC pts, a multidisciplinary treatment should be offered consisted of 4 cycles of cisplatin-based chemotherapy plus a 3(rd) generation cytotoxic agent or a cytostatic (anti-EGFR, anti-VEGFR) drug.

Keywords: Non-small cell lung cancer (NSCLC); lung cancer; targeted treatment; treatment.

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Figures

Figure 1
Figure 1
Treatment algorithm for NSCLC. (T, tumor; Ν, lymphnodes; Μ, metastasis).
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