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Review
. 2013 Oct 8;110(41):16287.
doi: 10.1073/pnas.1317033110.

Optogenetics

Sarah C P Williams  1 , Karl Deisseroth
Affiliations
Review

Optogenetics

Sarah C P Williams et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

None
By selectively inserting opsins—which react to light—into them, neurons can be activated or inactivated for research purposes. Image courtesy of Inbal Goshen and Karl Deisseroth.
See this image and copyright information in PMC

References

    1. Deisseroth K. Controlling the brain with light. Sci Am. 2010;303(5):48–55. - PubMed
    1. Oesterhelt D, Stoeckenius W. Rhodopsin-like protein from the purple membrane of Halobacterium halobium. Nat New Biol. 1971;233(39):149–152. - PubMed
    1. Matsuno-Yagi A, Mukohata Y. Two possible roles of bacteriorhodopsin; A comparative study of strains of Halobacterium halobium differing in pigmentation. Biochem Biophys Res Commun. 1977;78(1):237–243. - PubMed
    1. Harz H, Hegemann P. Rhodopsin-regulated calcium currents in Chlamydomonas. Nature. 1991;351(6326):489–491.
    1. Nagel G, et al. Channelrhodopsin-1: A light-gated proton channel in green algae. Science. 2002;296(5577):2395–2398. - PubMed

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