Proteolytic autodigestion: common tissue pathology in Shwachman-Diamond syndrome?

Affiliations

¹ Stem Cell Transplantation Program; Division of Pediatric Hematology/Oncology; Manton Center for Orphan Disease Research; Howard Hughes Medical Institute; Boston Children's Hospital and Dana Farber Cancer Institute; Department of Biological Chemistry and Molecular Pharmacology; Harvard Medical School; Broad Institute; Harvard Stem Cell Institute; Boston, MA USA.

Editorial

James M Kelley et al. Cell Cycle. 2013.

. 2013;12(22):3457-8.

doi: 10.4161/cc.26698. Epub 2013 Oct 8.

¹ Stem Cell Transplantation Program; Division of Pediatric Hematology/Oncology; Manton Center for Orphan Disease Research; Howard Hughes Medical Institute; Boston Children's Hospital and Dana Farber Cancer Institute; Department of Biological Chemistry and Molecular Pharmacology; Harvard Medical School; Broad Institute; Harvard Stem Cell Institute; Boston, MA USA.

No abstract available

Keywords: Shwachman-Diamond Syndrome; bone marrow failure; induced pluripotent stem cells; reprogramming.

Comment on

Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction.
Tulpule A, Kelley JM, Lensch MW, McPherson J, Park IH, Hartung O, Nakamura T, Schlaeger TM, Shimamura A, Daley GQ. Tulpule A, et al. Cell Stem Cell. 2013 Jun 6;12(6):727-36. doi: 10.1016/j.stem.2013.04.002. Epub 2013 Apr 18. Cell Stem Cell. 2013. PMID: 23602541 Free PMC article.

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