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. 2013 Dec;42(6):1752-1757.

doi: 10.1183/09031936.00140913. Epub 2013 Oct 10.

Neutrophilia independently predicts death in tuberculosis

David M Lowe^#^{1

2}, Asela K Bandara^#³, Geoffrey E Packe⁴, Richard D Barker⁵, Robert J Wilkinson^{1

2

6}, Christopher J Griffiths³, Adrian R Martineau^{3

1

6}

Affiliations

Affiliations

¹ Department of Medicine, Imperial College London, London W2 1PG, UK.
² Clinical Infectious Diseases Research Initiative, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, Cape Town, South Africa.
³ Blizard Institute, Barts and The London School of Medicine, Queen Mary University of London, London E1 2AB, UK.
⁴ Newham Chest Clinic, Forest Gate, London E7 8QP, UK.
⁵ Department of Respiratory Medicine, King's College Hospital, London SE5 9RS, UK.
⁶ Medical Research Council National Institute for Medical Research, London NW7 1AA, UK.

^# Contributed equally.

PMID: 24114967
PMCID: PMC4176760
DOI: 10.1183/09031936.00140913

Neutrophilia independently predicts death in tuberculosis

David M Lowe et al. Eur Respir J. 2013 Dec.

. 2013 Dec;42(6):1752-1757.

doi: 10.1183/09031936.00140913. Epub 2013 Oct 10.

Authors

David M Lowe^#^{1

2}, Asela K Bandara^#³, Geoffrey E Packe⁴, Richard D Barker⁵, Robert J Wilkinson^{1

2

6}, Christopher J Griffiths³, Adrian R Martineau^{3

1

6}

Affiliations

¹ Department of Medicine, Imperial College London, London W2 1PG, UK.
² Clinical Infectious Diseases Research Initiative, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, Cape Town, South Africa.
³ Blizard Institute, Barts and The London School of Medicine, Queen Mary University of London, London E1 2AB, UK.
⁴ Newham Chest Clinic, Forest Gate, London E7 8QP, UK.
⁵ Department of Respiratory Medicine, King's College Hospital, London SE5 9RS, UK.
⁶ Medical Research Council National Institute for Medical Research, London NW7 1AA, UK.

^# Contributed equally.

PMID: 24114967
PMCID: PMC4176760
DOI: 10.1183/09031936.00140913

No abstract available

PubMed Disclaimer

References

1. Lowe DM, Redford PS, Wilkinson RJ, O’Garra A, Martineau AR. Neutrophils in tuberculosis: friend or foe? Trends Immunol. 2012;33:14–25. - PubMed
1. Martineau AR, Newton SM, Wilkinson KA, Kampmann B, Hall BM, Nawroly N, Packe GE, Davidson RN, Griffiths CJ, Wilkinson RJ. Neutrophil-mediated innate immune resistance to mycobacteria. J Clin Invest. 2007;117:1988–94. - PMC - PubMed
1. Sugawara I, Udagawa T, Yamada H. Rat neutrophils prevent the development of tuberculosis. Infect Immun. 2004;72:1804–6. - PMC - PubMed
1. Nandi B, Behar SM. Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection. J Exp Med. 2011;208:2251–62. - PMC - PubMed
1. Brahmbhatt S, Black GF, Carroll NM, Beyers N, Salker F, Kidd M, Lukey PT, Duncan K, Van Helden P, Walzl G. Immune markers measured before treatment predict outcome of intensive phase tuberculosis therapy. Clin Exp Immunol. 2006;146:243–52. - PMC - PubMed

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