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Review
. 2013 Oct:1300:278-295.
doi: 10.1111/nyas.12253.

Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus

Kenneth DeVault  1 , Barry P McMahon  2 , Altay Celebi  3 , Guido Costamagna  4 , Michele Marchese  4 , John O Clarke  5 , Reza A Hejazi  6 , Richard W McCallum  6 , Vincenzo Savarino  7 , Patrizia Zentilin  8 , Edoardo Savarino  8 , Mike Thomson  9 , Rhonda F Souza  10 , Claire L Donohoe  11 , Naoimh J O'Farrell  11 , John V Reynolds  11
Affiliations
Review

Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus

Kenneth DeVault et al. Ann N Y Acad Sci. 2013 Oct.

Abstract

The following paper on gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) includes commentaries on defining esophageal landmarks; new techniques for evaluating upper esophageal sphincter (UES) tone; differential diagnosis of GERD, BE, and hiatal hernia (HH); the use of high-resolution manometry for evaluation of reflux; the role of fundic relaxation in reflux; the use of 24-h esophageal pH-impedance testing in differentiating acid from nonacid reflux and its potential inclusion in future Rome criteria; classification of endoscopic findings in GERD; the search for the cell origin that generates BE; and the relationship between BE, Barrett's carcinoma, and obesity.

Keywords: GERD; NERD; dysphagia; endoscopy; manometry.

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